Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications
A Retrospective Evaluation of the Effectiveness of Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications
Bagcilar Training and Research Hospital
230 participants
May 1, 2025
OBSERVATIONAL
Conditions
Summary
Study Description (For Patients, Families, and Healthcare Providers) Purpose: The aim of this study is to evaluate the effectiveness and safety of methotrexate treatment in women with ectopic pregnancy who belong to a group for whom this treatment is relatively contraindicated. Background: Methotrexate is a medication commonly used in the treatment of ectopic pregnancy (a pregnancy that occurs outside the uterus, usually in the fallopian tube). However, in certain conditions - such as kidney or liver dysfunction - methotrexate use may carry increased risks. These situations are known as relative contraindications. This study will retrospectively examine treatment outcomes in this specific patient population. Method: The study will analyze medical records of patients who were previously treated with methotrexate for ectopic pregnancy. No new interventions will be performed. The analysis will be based solely on existing clinical data. Why Is This Important? The findings of this study may help us better understand the safety limits of methotrexate therapy and guide healthcare providers in managing similar cases in the future.
Eligibility
Inclusion Criteria4
- Diagnosed with ectopic pregnancy
- Received methotrexate (MTX) treatment
- Underwent surgical treatment due to lack of response to MTX therapy
- Compliant with treatment follow-up
Exclusion Criteria2
- Participants with contraindications to methotrexate (MTX) treatment
- Participants non-compliant with follow-up
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Interventions
MTX medical treatment Laparoscopic salpingectomy Laparoscopic salpingostomy
Locations(1)
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NCT07186127