Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy
Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor-T Cell (CAR-T)Therapy
City of Hope Medical Center
190 participants
Jan 14, 2026
INTERVENTIONAL
Conditions
Summary
The overall purpose of this randomized control trial (RCT) is to determine the clinical effect of a multilevel, RPM-enhanced intervention during and after completion of outpatient CAR-T therapy in 190 patients and their family caregivers (FCGs).
Eligibility
Inclusion Criteria10
- Documented informed consent of the participant and/or legally authorized representative Age and Language Criteria
- Age ≥ 18 years old at the time of enrollment
- Ability to read and understand English or Spanish for Questionnaires Nature of Illness and Treatment Related Criteria
- Relapsed or refractory hematologic malignancy
- Scheduled to receive outpatient standard of care (SOC) CAR-T therapy
- Has a FCG committed to living with the patient for the duration of the study
- Documented informed consent of the participant and/or legally authorized representative Age and Language Criteria
- Age ≥ 18 years old at the time of enrollment
- Ability to read and understand English or Spanish for Questionnaires Nature of Illness and Treatment Related Criteria
- Family member or friend identified by the patient and defined as a person who knows the patient well and is involved in the patient's medical care
Exclusion Criteria1
- \-
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Patients and family caregivers that are randomized into the intervetnion arm (Digital health intervention) will receive a 90 day nurse-drive, digital health intervention. Participate in self-management coaching sessions
Wear a FitBit device and use a mobile app for nurse tracking
Ancillary studies
Given usual care
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07186192