RecruitingPhase 1NCT07186452

Evaluation of the Effect of Itraconazole on the Pharmacokinetics of HS-20093 in Patients With Advanced Solid Tumors

A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of HS-20093 in Patients With Advanced Solid Tumors Who Have Failed Adequate Standard Treatments or Are Intolerant to Standard Therapies


Sponsor

Hansoh BioMedical R&D Company

Enrollment

18 participants

Start Date

Sep 23, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The primary objective of this study is to evaluate the effect of itraconazole on the pharmacokinetics of HS-20093 in patients with advanced solid tumors.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called HS-20093 and a drug called Itraconazole for people with advanced solid tumors. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGHS-20093

All participants will receive intravenous infusion of HS-20093 at a dose of 8 mg/kg every 3 weeks (Q3W), with each treatment cycle lasting 21 days.

DRUGItraconazole

Participants will then take itraconazole capsules orally at 200 mg per dose during C2D17-C3D21


Locations(1)

Hunan Cancer Hospital

Changsha, Hunan, China

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NCT07186452


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