RecruitingNot ApplicableNCT07188064

A Study Looking at a New Nerve Surgery to Help Men Regain Erections After Prostate Cancer Surgery

Prospective Cohort Study of Somatic-Autonomic Nerve Grafting Technique to Restore Erectile Function in Patients With Persistent Erectile Dysfunction Post Radical Prostatectomy


Sponsor

Sir Mortimer B. Davis - Jewish General Hospital

Enrollment

100 participants

Start Date

Jan 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

A single arm prospective pilot trial evaluating the 1-year erectile recovery outcomes and the safety of patients undergoing a somatic to autonomic nerve grafting procedure for restoration of erectile function in patients who have lost erectile function following radical prostatectomy for prostate cancer. During this study a total of 100 patients who have persistent erectile dysfunction for more than 18 months post prostatectomy will undergo a post radical prostatectomy nerve restoration procedure (PRP-NR).


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a new nerve surgery to help men recover erections after having their prostate removed for cancer. Researchers want to see if this procedure can restore sexual function in men who haven't recovered on their own. **You may be eligible if...** - You are a man who had your prostate removed and have had significant trouble getting erections for at least 12–18 months afterward - You had good sexual function before your surgery - You are 18 or older **You may NOT be eligible if...** - It has been more than 5 years since your prostate surgery - You have diabetes with nerve damage or serious heart disease - You currently use hormone-blocking therapy (androgen deprivation therapy) - You already have a penile implant - You take medications for chronic nerve pain (such as gabapentin or pregabalin) - You have a mood disorder that has required a medication change in the last 3 months - You are not healthy enough for surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREPost radical prostatectomy nerve restoration procedure (PRP-NR)

Somatic to autonomic nerve grafting procedure which uses a nerve graft of ilioinguinal nerve harvested from the inguinal canal to perform a bilateral end to side junction between the dorsal penile nerve and the penile corpora cavernosa


Locations(1)

Jewish General Hospital

Montreal, Quebec, Canada

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07188064


Related Trials