RecruitingNCT07190183

Washed Microbiota Transplantation for Food Intolerance


Sponsor

The Second Hospital of Nanjing Medical University

Enrollment

100 participants

Start Date

Jan 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Food intolerance (FI) is an adverse reaction to food caused by non-immune mechanisms, mainly related to digestive enzyme deficiencies (e.g. lactase deficiency), metabolic abnormalities (e.g. impaired absorption of fructose) or toxicity of food components (e.g. histamine). Unlike immune-mediated food allergy, FI symptoms are usually delayed (hours to days after ingestion) and mild, but are difficult to diagnose and manage clinically due to the complexity and variety of mechanisms that affect approximately 20% of the world's population.


Eligibility

Inclusion Criteria2

  • Food intolerance occurs through laboratory examination of at least two main foods
  • Underwent washed microbiota transplantation.

Exclusion Criteria3

  • Expected survival time \<3 months;
  • Women who are pregnant or breastfeeding;
  • Other patients deemed not suitable for enrollment by the investigator.

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Interventions

PROCEDUREwashed microbiota transplantation

The prepared microbiota suspension was infused into the patients' gut.


Locations(1)

Department of Microbiota Medicine & Medical Centre for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, China

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NCT07190183


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