Washed Microbiota Transplantation for Food Intolerance
The Second Hospital of Nanjing Medical University
100 participants
Jan 1, 2025
OBSERVATIONAL
Conditions
Summary
Food intolerance (FI) is an adverse reaction to food caused by non-immune mechanisms, mainly related to digestive enzyme deficiencies (e.g. lactase deficiency), metabolic abnormalities (e.g. impaired absorption of fructose) or toxicity of food components (e.g. histamine). Unlike immune-mediated food allergy, FI symptoms are usually delayed (hours to days after ingestion) and mild, but are difficult to diagnose and manage clinically due to the complexity and variety of mechanisms that affect approximately 20% of the world's population.
Eligibility
Inclusion Criteria2
- Food intolerance occurs through laboratory examination of at least two main foods
- Underwent washed microbiota transplantation.
Exclusion Criteria3
- Expected survival time \<3 months;
- Women who are pregnant or breastfeeding;
- Other patients deemed not suitable for enrollment by the investigator.
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Interventions
The prepared microbiota suspension was infused into the patients' gut.
Locations(1)
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NCT07190183