Ginger to Prevent Nausea and Vomiting After Laparoscopic Cholecystectomy
Preoperative Ginger for the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy: A Double-Blind Randomized Controlled Trial
University Tunis El Manar
102 participants
Jul 5, 2025
INTERVENTIONAL
Summary
This study aims to evaluate whether preoperative oral administration of ginger (800 mg, given 2 hours before surgery) reduces the incidence and severity of postoperative nausea and vomiting (PONV) within the first 24 hours after laparoscopic cholecystectomy.
Eligibility
Inclusion Criteria4
- Age ≥ 18 years.
- Scheduled for elective laparoscopic cholecystectomy under general anesthesia.
- American Society of Anesthesiologists (ASA) physical status I-III.
- Able to understand the study procedures and provide written informed consent.
Exclusion Criteria6
- Known allergy or hypersensitivity to ginger
- Documented history of bleeding disorders or current treatment with anticoagulant agents
- History of severe postoperative nausea and vomiting or an Apfel score of 4
- Administration of antiemetic drugs or corticosteroids during the preoperative period
- Pregnancy or breastfeeding
- Active gastrointestinal or liver disease
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Interventions
Patients will receive 800 mg of oral ginger 2 hours before laparoscopic cholecystectomy
Patients will receive an oral placebo capsule identical in appearance to ginger, administered 2 hours before laparoscopic cholecystectomy
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07190495