A Study of MHB048C in Patients With Advanced Solid Tumors

This study is testing a new drug called MHB048C for adults with advanced solid tumors (any type) that have not responded to standard treatments. This is an early-phase study focused on safety and finding the right dose. **You may be eligible if...** - You are 18 or older - You have a confirmed advanced solid tumor that has stopped responding to standard therapy, that you could not tolerate, or for which no standard treatment exists - You have at least one measurable tumor on imaging - You are well enough to participate (ECOG 0 or 1) - Your life expectancy is at least 3 months - Your blood counts and organ function are adequate **You may NOT be eligible if...** - You have had two or more separate cancers within the past 5 years - You recently received chemotherapy (within 3 weeks) or other cancer therapy (within 4 weeks) - You have brain, bone marrow, or spinal cord involvement from cancer - You have had recent vaccinations, serious infections, or significant bleeding - You are pregnant or breastfeeding - You have serious heart, lung, or cardiovascular disease - You have a known allergy to the study drug Talk to your doctor to see if this trial is right for you.