Zinc Oxide VS MEBO

Exclusion Criteria9

• Not consenting to participate
• Patients with suspected hypersensitivity reactions to any of the topical formulation's ingredients.
• Either a category III or IV pressure ulcer.
• Evidence of deep tissue injury (exudative drainage, purple or maroon localized area of discolored intact skin or blood-filled blister due to pressure damage).
• Signs of wound infection (pus draining from the ulcer, a foul-smelling odour, tenderness, heat and increased redness in the surrounding skin and fever).
• Patients who undertaking other therapies that could affect healing, such as corticosteroids, radiation therapy, or chemotherapy for cancer.
• Heavy smoking (more than 20 cigarettes a day).
• Concomitant chronic disease (e.g., diabetes mellitus or frank vascular disease such as Buerger's disease).
• Patients who unable to continue the study because of death, discharge, or change in the care setting.