RecruitingNot ApplicableNCT07195305

Radiofrequency Endometrial Ablation or Uterine Artery Embolization for Treatment of Adenomyosis-related Abnormal Uterine Bleeding

Radiofrequency Endometrial Ablation or Uterine Artery Embolization for Women With Adenomyosis-related Abnormal Uterine Bleeding Eligible for Hysterectomy: a Non-inferiority Randomized Clinical Trial Comparing Each Intervention to Hysterectomy

Sponsor

University Hospital, Bordeaux

Enrollment

230 participants

Start Date

Apr 17, 2026

Study Type

INTERVENTIONAL

Conditions

Abnormal Uterine Bleeding Due to Adenomyosis (Disorder)

Summary

The present study aims to compare the efficacy (menstrual blood loss, pain, quality of life) and the safety (complications, recovery) of each conservative intervention (RFA, UAE) versus hysterectomy for the treatment of adenomyosis-related abnormal uterine bleeding, up to 2 years

Eligibility

Sex: FEMALEMin Age: 30 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Hysterectomy, a procedure called Radiofrequency endometrial ablation, and others for people with abnormal uterine bleeding due to adenomyosis (disorder). The study is currently recruiting participants at 4 locations. People eligible for this study include women aged 30 Years to 50 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURERadiofrequency endometrial ablation

Radiofrequency endometrial ablation

PROCEDUREUterine artery embolization

Uterine artery embolization

PROCEDUREHysterectomy

Hysterectomy

Locations(4)

CHU Bordeaux

Bordeaux, France

APHP - Hôpital Antoine Béclère

Clamart, France

CHU Limoges

Limoges, France

CHU Montpellier

Montpellier, France

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NCT07195305