RecruitingPhase 2Phase 3NCT07199504

A Self-Controlled Study on the Treatment of Restless Legs Syndrome in Uremia With Dipyridamole


Sponsor

Yunfeng Xia

Enrollment

80 participants

Start Date

Sep 20, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this clinical trial is to determine whether dipyridamole can treat restless legs syndrome in patients with uremia. In addition, the safety of dipyridamole will also be evaluated. The main questions this study aims to answer include: Can dipyridamole improve the symptoms of restless legs syndrome in participants? Can dipyridamole improve participants' anxiety, depression, sleep quality, and quality of life? What adverse reactions might participants experience while taking dipyridamole? This study is a self-controlled trial in which all participants receive active drug treatment. Participants will take dipyridamole daily (50 mg per dose, three times a day) for 12 weeks. The efficacy of dipyridamole will be evaluated by comparing relevant scale scores and laboratory indicators before and after treatment. In addition, adverse reactions during the treatment follow-up will be monitored to assess the safety of dipyridamole in this patient population.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Dipyridamole 50mg tid for people with restless leg syndrome due to uraemia. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDipyridamole 50mg tid

Participants will take dipyridamole daily (50mg each time, three times a day) for 12 weeks


Locations(1)

First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

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NCT07199504