RecruitingPhase 2NCT07201051

A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis

A Phase 2 Randomized, Double-blind, Placebo-controlled Study to Investigate Efficacy, Safety, Immunogenicity, and Pharmacokinetics, of GSK3862995B in Participants With Bronchiectasis


Sponsor

GlaxoSmithKline

Enrollment

446 participants

Start Date

Oct 30, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study is designed to find out how effective and safe a new drug, GSK3862995B, is for adult participants with bronchiectasis, a chronic lung disease. The study will also test how the body processes the drug and to check for any immune reactions. Participants will be divided into groups randomly to receive either one of two different doses of the study drug or a placebo. The main goal of the study is to see how well the drug works compared to the placebo in helping those with bronchiectasis.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called GSK3862995B and a drug called Placebo for people with bronchiectasis. The study is currently recruiting participants at 39 locations. People eligible for this study include aged 18 Years to 85 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGGSK3862995B

Participants will be administered with dose level 1 of GSK3862995B.

DRUGPlacebo

Participants will be administered with matching placebo.


Locations(39)

GSK Investigational Site

Mobile, Alabama, United States

GSK Investigational Site

La Palma, California, United States

GSK Investigational Site

Miami, Florida, United States

GSK Investigational Site

Miami, Florida, United States

GSK Investigational Site

Naples, Florida, United States

GSK Investigational Site

Plantation, Florida, United States

GSK Investigational Site

St. Petersburg, Florida, United States

GSK Investigational Site

Rockville, Maryland, United States

GSK Investigational Site

DuBois, Pennsylvania, United States

GSK Investigational Site

Anderson, South Carolina, United States

GSK Investigational Site

Rock Hill, South Carolina, United States

GSK Investigational Site

Spartanburg, South Carolina, United States

GSK Investigational Site

Conroe, Texas, United States

GSK Investigational Site

Sugar Land, Texas, United States

GSK Investigational Site

Beijing, China

GSK Investigational Site

Chongqing, China

GSK Investigational Site

Guangzhou, China

GSK Investigational Site

Guangzhou, China

GSK Investigational Site

Hangzhou, China

GSK Investigational Site

Huizhou, China

GSK Investigational Site

Jiangmen, China

GSK Investigational Site

Jiangsu, China

GSK Investigational Site

Nanjing, China

GSK Investigational Site

Qingyuan, China

GSK Investigational Site

Weifang, China

GSK Investigational Site

Yangzhou, China

GSK Investigational Site

Zhanjiang, China

GSK Investigational Site

Frankfurt, Germany

GSK Investigational Site

Ashdod, Israel

GSK Investigational Site

Ashkelon, Israel

GSK Investigational Site

Beersheba, Israel

GSK Investigational Site

Haifa, Israel

GSK Investigational Site

Jerusalem, Israel

GSK Investigational Site

Jerusalem, Israel

GSK Investigational Site

Kfar Saba, Israel

GSK Investigational Site

Koranit, Israel

GSK Investigational Site

Petah Tikva, Israel

GSK Investigational Site

Tel Aviv, Israel

GSK Investigational Site

Kanagawa, Japan

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT07201051


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