Assessment of Skin Lesions Using a Tissue Oxygen Imager Based on Protoporphyrin IX (PPIX) Fluorescence. This is an Open-label, Non-randomized, Feasibility Study That Includes a One-time Application of an FDA Approved Medication Followed by Local Imaging for Benign Skin Growth and Lesions Clinically

This feasibility study is testing a new imaging technique that uses a special light-sensitive chemical (protoporphyrin IX) and a tissue oxygen imaging device to better visualize and assess non-melanoma skin cancer (such as basal cell carcinoma or squamous cell carcinoma) before surgical removal. **You may be eligible if...** - You are 18 or older - You have been confirmed to have non-melanoma skin cancer by a tissue biopsy - Your skin lesion measures between 5 mm and 3 cm - You are scheduled for surgical removal of the lesion - If you are a woman of childbearing age, you have a negative pregnancy test within 7 days before the study **You may NOT be eligible if...** - You are under 18 years old - You are unable to understand or follow study procedures - You are pregnant or breastfeeding - You have a known allergy to the topical medication used in the imaging Talk to your doctor to see if this trial is right for you.