RecruitingNot ApplicableNCT07206017

Explorative Study on Addition of High-fiber Dried Chicory Root in Patients With an Intermediate to High-risk Cutaneous Melanoma.

Measuring Effects of High-fiber Dried Chicory Root on the Gut Microbiota of Patients With an Intermediate to High-risk Cutaneous Melanoma: an Explorative Study


Sponsor

University Medical Center Groningen

Enrollment

20 participants

Start Date

Mar 26, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Exploring the effect of supplementation with daily addition of prebiotic dried chicory root (WholeFiberTM) for 6 weeks on fecal SCFA levels, gut microbial composition and immune cell composition in minimal stage II A melanoma patients following surgical treatment.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether adding a high-fiber dried chicory root supplement to the diet — after surgical removal of an intermediate to high-risk skin melanoma — can improve the gut microbiome (the community of bacteria in your gut) and potentially support the immune system in preventing the cancer from returning. **You may be eligible if...** - You are 18 or older - You have had surgery to remove an intermediate or high-risk melanoma (specific staging criteria apply) - There is no evidence that the cancer has spread - You are not currently receiving any other adjuvant (post-surgery) cancer treatment - You can read and speak Dutch and are willing to attend study visits **You may NOT be eligible if...** - You are currently receiving adjuvant cancer therapy (treatment after surgery) - You have diabetes, heart disease, kidney disease, or autoimmune conditions - You have gut conditions like inflammatory bowel disease, celiac disease, or short bowel syndrome - You have an ileostomy or colostomy - You have used antibiotics in the last 3 months - You are taking immunosuppressive medications or steroids - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERprebiotic dried chicory root (WholeFiber)

Supplementing with WholeFiber for 6 weeks two times a day (10 g per portion).


Locations(1)

UMCG

Groningen, Provincie Groningen, Netherlands

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07206017