Effectiveness of Ultrasound-Guided Versus Traditional IV Insertion by Oncology Nurses in Adult Population Recieving Systemic Anti-cancer Therapy
Effectiveness of Ultrasound-guided Peripheral Intravenous Catheter (EUPIC) Insertion Versus Traditional (Touch and Feel) Insertion Approaches by Oncology Nurses. A Mixed-methods Randomized Controlled Trial (RCT)
University of Galway
98 participants
Oct 20, 2025
INTERVENTIONAL
Conditions
Summary
What is this study about? This study is comparing two different methods nurses use to place an intravenous (IV) drip, which is needed for many cancer treatments. Traditional method: The nurse finds a vein by touch and sight. Ultrasound-guided method: The nurse uses a small, handheld ultrasound scanner to see the vein under the skin to help guide the needle. Why is it important? Sometimes it can take more than one attempt to get an IV drip in place, which can be uncomfortable. For cancer patients, whose veins can be more fragile, this is a common challenge. This research will help us find out if using ultrasound helps get the IV in successfully on the first try more often, which can make the treatment experience better. What does participation involve? If you choose to take part, you will be randomly assigned (like a coin toss) to have your IV placed with either the traditional method or the ultrasound method. The research team will then collect some information about the IV placement. Your participation is entirely voluntary and will not affect your standard medical care.
Eligibility
Inclusion Criteria4
- Adults aged 18 years or older.
- Diagnosed with cancer (all cancer sites eligible).
- Scheduled to receive systemic anti-cancer therapy (SACT) such as chemotherapy, immunotherapy, or targeted therapies.
- Requiring peripheral intravenous catheter (PIVC) insertion for treatment.
Exclusion Criteria3
- Patients younger than 18 years.
- Individuals unable to provide informed consent.
- Individuals unable to cooperate with study procedures (e.g., cognitive or physical limitations preventing adherence).
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Interventions
In this arm, PIVC insertion is performed by oncology nurses who have completed a structured ultrasound training program. Nurses use real-time ultrasound imaging to identify and select a suitable vein, guide the advancement of the catheter, and confirm placement. This method contrasts with the standard touch-and-feel approach by incorporating ultrasound technology and specialized nurse training to improve first-time insertion success and reduce complications.
PIVC insertion performed by oncology nurses using the conventional touch-and-feel landmark technique, relying on visual inspection and palpation of veins. Represents current standard clinical practice in oncology.
Locations(2)
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NCT07208175