Prospective Evaluation of the Treatment of Cancer Associated Superficial Venous
Centre Hospitalier Universitaire, Amiens
1,576 participants
Nov 10, 2025
OBSERVATIONAL
Conditions
Summary
Superficial venous thrombosis (SVT) is very common in clinical practice. What's more, around 15- 20% of SVTs occur in the context of cancer. Today, cancer patients are excluded from therapeutic trials for DVT. There is therefore no high-level evidence-based treatment recommendation for these patients. Recent data suggest that the course of cancer-associated DVT is similar to that of cancer-associated deep vein thrombosis (DVT). However, there are currently few prospective data on the evolution of cancer-associated DVT in relation to the treatment used. Due to the absence of clear recommendations of treatment in case of SVT associated with cancer the investigators will perform a prospective observational study to evaluate the efficacy of different regiment of anticoagulant treatment ordered in clinical practice.
Eligibility
Inclusion Criteria9
- Patient over 18
- Patient affiliated to a social security scheme
- Patient who understands French
- Patient with superficial venous thrombosis of the lower and upper limbs confirmed by a Doppler ultrasound less than one month old.
- Patient with active cancer:
- Cancer treatment within the last 6 months,
- Detectable tumor disease, cancer treatment within the last 6 months, ongoing hormone therapy for cancer, palliative cancer.
- The patient has received potentially non-curative cancer treatment (notably palliative chemotherapy).
- Progression shows that the cancer treatment was not curative (due to recurrence or progression under treatment) (particularly in the case of recurrence after surgery)
Exclusion Criteria6
- Patients under legal protection
- Patients with concomitant pulmonary embolism
- Patient with proximal or distal deep vein thrombosis
- Patient treated with anticoagulant therapy for another indication
- Patient with a contraindication to anticoagulation: Thrombocytopenia less than 30,000 elements/mm3, active bleeding or history of severe bleeding.
- Patient opposed to participation in research
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07210671