RecruitingNot ApplicableNCT07210762

Gingival Cleft Development at Two Time Points of Canine Retraction

Gingival Cleft Development at Two Time Points of Canine Retraction: a Split-mouth Randomized Controlled Trial


Sponsor

Bahria University

Enrollment

19 participants

Start Date

Oct 15, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this split-mouth randomized controlled trial is to assess whether the timing of extraction space closure-early vs. delayed initiation-affects the incidence of gingival cleft development in orthodontic patients. The main question it aims to answer is: Does the incidence of gingival cleft development get influenced by the specific time point at which orthodontic space closure is initiated following extraction? Quadrants will be assigned to the early movement group and the other to the delayed movement group and extractions will be performed accordingly. These will be assessed for the effect on development of gingival cleft development.


Eligibility

Inclusion Criteria2

  • Extraction advised of both first premolars from either maxilla, mandible or both.
  • All permanent dentition present apart from third molars.

Exclusion Criteria6

  • Severe crowding
  • Smokers
  • Patients with systemic diseases that could interfere with bone remodeling.
  • Patients with periodontitis or poor periodontal health.
  • Patients who have previously undergone periodontal surgery in the area of interest.
  • Patients with other oral health conditions that could complicate the treatment or healing process.

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Interventions

OTHEREarly space closure

Space closure will be started 1 week after extraction

OTHERDelayed space closure

Space closure will be started 8 weeks after extraction


Locations(1)

Bahria University of Health Sciences Karachi

Karachi, Sindh, Pakistan

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NCT07210762