RecruitingPhase 3NCT07211776

A Study to Assess the Efficacy and Safety of ZL-1109 in Chinese Participants With Active Thyroid Eye Disease

A Multicenter, Double-blinded, Randomized, Placebo Controlled Phase 3 Trial to Evaluate the Efficacy and Safety of ZL-1109 in Chinese Participants With Thyroid Eye Disease (TED)


Sponsor

Zai Lab (Shanghai) Co., Ltd.

Enrollment

99 participants

Start Date

Dec 5, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

A Multicenter, Double-blinded, Randomized, Placebo-controlled Phase 3 Study of ZL-1109 in Chinese Participants with Thyroid Eye Disease (TED)


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo and a drug called ZL-1109 (VRDN-003) for people with thyroid eye disease (ted). The study is currently recruiting participants at 27 locations. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGZL-1109 (VRDN-003)

ZL-1109 subcutaneous injection

DRUGPlacebo

Matching placebo subcutaneous injection


Locations(27)

Site01006

Beijing, China

Site01009

Beijing, China

Site01010

Beijing, China

Site01029

Bengbu, China

Site01020

Changsha, China

Site01022

Chengdu, China

Site01031

Chongqing, China

Site01011

Dalian, China

Site01008

Foshan, China

Site01004

Fuzhou, China

Site01007

Guangzhou, China

Site01027

Guiyang, China

Site01018

Hangzhou, China

Site01002

Hefei, China

Site01024

Jinan, China

Site01005

Luoyang, China

Site01017

Nanchang, China

Site01001

Shanghai, China

Site01012

Shenyang, China

Site01023

Taiyuan, China

Site01013

Tianjin, China

Site01016

Wuxi, China

Site01028

Xi'an, China

Site01025

Xuzhou, China

Site01026

Yangzhou, China

Site01019

Zhengzhou, China

Site01030

Zhengzhou, China

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NCT07211776


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