RecruitingNot ApplicableNCT07212361

Infant Microbiota Restoration With Maternal Microbes


Sponsor

University of Helsinki

Enrollment

100 participants

Start Date

Jul 17, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to test the ability of different bacterial products in restoring natural gut microbiota in C-section born infants. The main question it aims to answer is: Do maternally derived strains of bacteria perform better than commercially available probiotic strains in restoring the gut microbiota of C-section born infants? Researchers will compare the gut microbiota of treated infants to that of untreated C-section born infants and untreated vaginally born infants to see if the bacterial treatments cause the microbiota to resemble that of vaginally born infants. Participants will be given a bacterial product orally once daily for either one or four weeks and be asked to collect faecal, urine and saliva samples.


Eligibility

Max Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Placebo and Probiotic for people with cesarean delivery affecting newborn, cesarean section, and other related conditions. The study is currently recruiting participants at 2 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTProbiotic

Specific infant-adapted commercially available strains or strains isolated from the infant's mother.

OTHERPlacebo

Infant formula without bacteria.


Locations(2)

Helsinki University Hospital

Helsinki, Finland

University of Helsinki

Helsinki, Finland

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NCT07212361


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