Clinical Study to Investigate the Antihypersensitivity Efficacy of a Novel Dentifrice

Exclusion Criteria15

• Female participant who is pregnant at Screening and Baseline, or is intending to become pregnant during the study.
• Female participant who is breastfeeding.
• Participant with known or suspected intolerance or hypersensitivity to any of the study products, any of their stated ingredients or closely related compounds.
• Participant is participating in, or has participated in, other studies (including non-medicinal studies) involving an Investigational Product within 30 days of Screening or plans to participate in other studies (including non-medicinal studies) during this study.
• Participant has participated in a tooth sensitivity study within 8 weeks of Screening.
• Participant is currently using an oral care product indicated for dentin hypersensitivity relief or care of sensitive teeth or has used an antihypersensitivity oral care product within 8 weeks of Screening.
• Participant takes daily doses of medications/treatments which, in the opinion of the investigator or medically qualified designee, could interfere with their perception of tooth sensitivity.
• Participant has had professional tooth de-sensitising treatment within 8 weeks of Screening.
• Participant has had a tooth bleaching procedure within 8 weeks of Screening.
• Participant has had dental prophylaxis within 4 weeks of Screening.
• Participant with evidence of gross intra-oral neglect or the need for extensive dental therapy.
• Participant with evidence of current/recent active dental caries or treatment for decay within 12 months of Screening.
• Participant who, in the opinion of the investigator or dentally qualified designee, is at high risk of dental caries.
• Participant with specific dentition exclusions for 'Test Teeth'.
• Participant has taken antibiotics in the 2 weeks prior to Screening or Baseline.