Dopamine and Sensorimotor Function in Stuttering
University of California, San Francisco
40 participants
Sep 30, 2025
INTERVENTIONAL
Conditions
Summary
This study is being done to understand the effect of aripiprazole on adults who stutter. Stuttering is a disorder that affects speech fluency. This study aims to understand sensorimotor pathways of stuttering and possible interventions.
Eligibility
Inclusion Criteria5
- native speakers of American English
- for adults who stutter, presence of stuttering will be confirmed, with onset before age 6 years
- Normal hearing
- Ages of 18 to 65 years
- healthy adults without hearing-language difficulties
Exclusion Criteria3
- self-reported speech-language-hearing difficulties other than stuttering
- self-reported neurological or psychological problems
- other medications (drugs that affect dopaminergic system and/or benzodiazepines)
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Interventions
The effects of aripiprazole on stuttering and various behavioral and neural outcomes will be studied compared to placebo.
Placebo will be compared against aripiprazole for effect on stuttering and various behavioral and neural markers.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07215884