RecruitingPhase 1NCT07217886

A Study of S-892216-PO in Participants With Renal Impairment and Matched Controls

A Phase 1, Multicenter, Nonrandomized, Open-label, Parallel-group Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of S-892216-PO in Participants With Varying Degrees of Renal Impairment and Matched Control Participants With Normal Renal Function


Sponsor

Shionogi

Enrollment

40 participants

Start Date

Oct 16, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to measure the pharmacokinetics, safety, and tolerability of S-892216 (S-892216-PO) in participants with mild, moderate, or severe renal impairment not on dialysis, or renal impairment requiring hemodialysis (HD), and in participants with normal renal function.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called S-892216-PO for people with renal impairment. The study is currently recruiting participants at 4 locations. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGS-892216-PO

S-892216-PO tablet will be administered orally.


Locations(4)

Orlando Clicinal Research Center

Orlando, Florida, United States

Global Clinical Professionals (GCP) LLC

St. Petersburg, Florida, United States

Genesis Clinical Research

Tampa, Florida, United States

Alliance for Multispecialty Research (AMR)-Knoxville

Knoxville, Tennessee, United States

View Full Details on ClinicalTrials.gov

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NCT07217886


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