Using E-Nose Technology to Track Treatment Response in People With Non-Small Cell Lung Cancer

This study is testing whether an "electronic nose" — a device that analyzes the chemical composition of exhaled breath — can track how well treatment is working in people with non-small cell lung cancer (NSCLC). By detecting changes in breath patterns, the device may offer a painless, non-invasive way to monitor cancer treatment responses. **You may be eligible if...** - You are 18 or older - You have untreated early-stage (Stage I) non-small cell lung cancer that can be treated with surgery - OR you have untreated Stage II to IIIB NSCLC planned for chemotherapy before surgery (neoadjuvant treatment) - You are well enough to undergo treatment (ECOG performance status 0 to 2) **You may NOT be eligible if...** - You have already started treatment for your lung cancer - Your cancer is at a stage not eligible for surgery - Your general health is too poor to participate Talk to your doctor to see if this trial is right for you.