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RecruitingNot ApplicableNCT07219992

Parent-Based Treatment for Adolescent Anxiety

Testing a Novel Parent-Based Treatment for Adolescent Anxiety Disorders

Sponsor

Yale University

Enrollment

108 participants

Start Date

Nov 1, 2025

Study Type

INTERVENTIONAL

Conditions

Anxiety Disorder of Adolescence

Summary

This study aims to test the efficacy of a parent-only approach to treating anxiety disorders in adolescents: SPACE (Supportive Parenting for Anxious Childhood Emotions). The comparator is another parent-based approach, PES (Parent Education and Support). The study design is a randomized controlled trial with 2 treatment arms and 3 assessment points (pre, post, and follow-up) using questionnaire data and clinical interviews.

Eligibility

Min Age: 14 YearsMax Age: 17 Years

Inclusion Criteria4

  • Meet criteria for a primary DSM-5 AD, including separation anxiety disorder, social anxiety disorder, generalized anxiety disorder, specific phobia, panic disorder, and agoraphobia (determined by the ADIS-C/P).
  • Cease all other psychosocial treatment, upon consultation with the project staff and service provider.
  • Not currently use any psychotropic medication, other than a stable dose (i.e., same dose for a minimum of 6 months prior to enrollment; no changes during course of the study) of a stimulant medication or selective serotonin reuptake inhibitor (SSRI).
  • Have an eligible and willing participating parent (see parent exclusions below).

Exclusion Criteria10

  • Adolescent:
  • Meet criteria for any DSM-5 disorder more impairing than the most impairing AD (determined by the ADIS-C/P).
  • Have any of the following disorders: autism spectrum disorder; intellectual disability; neurocognitive disorders; bipolar disorder; schizophrenia and other psychotic disorders; and alcohol and substance use disorders (determined by the Health History Form and ADIS-C/P).
  • Report a suicide attempt in the last 3 months, or current suicide intent and plans (determined by the ASQ).
  • Be a victim of past or present undisclosed abuse requiring investigation or ongoing supervision by the Department of Social Services.
  • Not have sufficient proficiency with the English language to complete assessments.
  • Parents:
  • Have any of the following: intellectual disability; neurocognitive disorders; untreated bipolar disorder; untreated schizophrenia and other psychotic disorders; and untreated alcohol and substance use disorders (determined by the Health History Form).
  • Not be living with the adolescent at least 50% of the time for at least one year prior to enrollment.
  • Not have sufficient proficiency with the English language to complete assessments and treatment.

Interventions

BEHAVIORALSupportive Parenting for Anxious Childhood Emotions (SPACE)

Parent based treatment delivered by a therapist 12 weekly sessions with parents.

BEHAVIORALParent Educational Support (PES)

Parent Educational Support: 12 weekly sessions with parents

Locations(1)

Yale Child Study Center

New Haven, Connecticut, United States

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NCT07219992