RecruitingPhase 3NCT07226232

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

A Multi-site Randomized Controlled Trial of Psilocybin for Treatment-Resistant Depression (TRD) in Veterans

Sponsor

VA Office of Research and Development

Enrollment

240 participants

Start Date

Aug 3, 2026

Study Type

INTERVENTIONAL

Conditions

Major Depression

Summary

The purpose of this multi-site randomized controlled trial is to evaluate the efficacy and risks of psilocybin for the treatment of depression in U.S. military Veterans with and without (±) concurrent posttraumatic stress disorder.

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Psilocybin and a drug called Psilocybin for people with major depression. The study is currently recruiting participants at 5 locations. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.