RecruitingNCT07226804

Nanosecond Pulsed Field Ablation in the Management of Benign Thyroid Nodules


Sponsor

M.D. Anderson Cancer Center

Enrollment

30 participants

Start Date

Nov 14, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

To observe the outcomes of nsPFA therapy to treat benign thyroid nodules.


Eligibility

Min Age: 18 Years

Inclusion Criteria11

  • Eligibility Criteria
  • Scheduled to undergo ultrasound guided nsPFA as standard of care
  • Age 18 to 80 years.
  • Capable of providing independent consent.
  • Presence of biopsy-confirmed benign thyroid nodule , defined as one of the following:
  • Benign FNA X 2 or
  • Benign US guided FNA X 1 + benign thyroid nodule ultrasound appearance (TI-RADS 2) or
  • Benign FNA X 1 and radiographic/laboratory evidence of functional nature
  • Nodule measuring >2cm in greatest dimension
  • Presence of compressive symptoms reasonably attributable to thyroid nodule (i.e. pressure sensation, dysphagia, dysphonia, respiratory distress)
  • No abnormal cervical lymph nodes during screening visit .

Exclusion Criteria2

  • Age <18
  • Patients considered unsuitable for nsPFA by the treating physician

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Interventions

OTHERQuestionnaire

patient-reported outcomes questionnaire


Locations(1)

MD Anderson Cancer Center

Houston, Texas, United States

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NCT07226804


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