AI for Onsite Cytology Evaluation in Endoscopic Ultrasound

This study tests whether the AI platform ChatGPT can accurately interpret cytology (cell) samples from endoscopic ultrasound-guided biopsies (EUS-FNB) of solid masses in the gastrointestinal tract, with the goal of determining if AI could substitute for an on-site cytopathologist during the procedure. Rapid on-site evaluation by a cytopathologist improves biopsy accuracy, but this expertise is not available at most centers. Eligible participants are adults aged 18 and older who are already scheduled to undergo EUS-guided fine needle biopsy of a solid gastrointestinal mass lesion; patients with only cystic lesions are excluded. Participation involves having the biopsy performed as planned, with cytology images also analyzed by ChatGPT and compared against the pathologist's interpretation. This summary was prepared using AI to help patients understand the study in plain language.