RecruitingNCT07230236

Relationship Between LS Chirp ABR and Speech-in-Noise Skills in Hidden Hearing Loss

Investigation of the Relationship Between LS Chirp ABR and Comprehension In Noise Skills In Individuals With Suspected Hidden Hearing Loss


Sponsor

Istanbul University - Cerrahpasa

Enrollment

63 participants

Start Date

Aug 20, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

It is known that the underlying problem in Hidden Hearing Loss (HHL) is cochlear synaptopathy (CS) and that low-spontaneous-rate auditory nerve fibers play an important role in this pathology. Therefore, it is suggested that low-spontaneous-rate auditory nerve fibers are damaged in HHL. Consequently, LS CE-Chirp-evoked ABR and HINT, which assesses CS by presenting stimuli of varying intensities and characteristics to provide information about auditory nerve fibers, will be used to evaluate participants both objectively and subjectively. Aim of the study: The main aim of this study is to investigate the relationship between the amplitude and latency values obtained with LS CE-Chirp-stimulated ABR and the critical Signal-to-Noise Ratio (SNR) obtained from the Hearing in Noise Test (HINT) in individuals suspected of having HHL. Hypotheses H0: In individuals suspected of having HHL, there is no relationship between the amplitude values of waves I, III, and V obtained with LS CE-Chirp ABR at 80, 90, and 100 dBnHL and the I/V amplitude ratio and the critical SNR obtained from HINT. H1: In individuals suspected of having HHL, there is a relationship between the amplitude values of waves I, III, and V obtained with LS CE-Chirp ABR at 80, 90, and 100 dBnHL and the I/V amplitude ratio, and the critical SNR obtained from HINT. Expected Results: The study will reveal how LS CE-Chirp stimulation affects ABR results in individuals suspected of having HHL, and the relationship between these results and HINT results will be examined. In this way, HHL will be evaluated both objectively (LS CE-Chirp ABR) and subjectively (HINT). Based on the findings, scientific outputs such as publications or projects are targeted. Importance: HHL has recently attracted increasing attention as a condition that significantly affects daily life. In today's world, where noise and noisy environments are prevalent, disadvantages arise in many aspects, particularly in communication. Therefore, the findings obtained in this study may contribute to a better understanding of HHL.


Eligibility

Min Age: 20 YearsMax Age: 60 Years

Inclusion Criteria16

  • Being between 20 and 60 years of age,
  • Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL),
  • Having no tinnitus or auditory complaints,
  • Scoring 21 or above on the MoCA test,
  • Having no emotional or neurological problems that could interfere with the tests.
  • Being between 20 and 60 years of age,
  • Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL),
  • Having a chronic tinnitus complaint (≥3 months),
  • Scoring 21 or above on the MoCA test,
  • Having no emotional or neurological problems that could interfere with the tests.
  • Being between 20 and 60 years of age,
  • Having bilateral pure-tone audiometry averages (500-1000-2000-4000 Hz) within the normal range (≤25 dB HL),
  • Having no chronic tinnitus complaint,
  • Having an average score below 4.3 on the "Speech Perception" subscale of the Speech, Spatial and Qualities of Hearing Scale (SSQ),
  • Scoring 21 or above on the MoCA test,
  • Having no emotional or neurological problems that could interfere with the tests.

Exclusion Criteria9

  • Presence of peripheral and/or central hearing loss,
  • Presence of somatosensory tinnitus,
  • Presence of emotional and/or neurological problems that could interfere with the tests.
  • Presence of peripheral and/or central hearing loss,
  • Presence of somatosensory tinnitus,
  • Presence of emotional and/or neurological problems that could interfere with the tests.
  • Presence of peripheral and/or central hearing loss,
  • Presence of somatosensory tinnitus,
  • Presence of emotional and/or neurological problems that could interfere with the tests.

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Locations(1)

Istanbul University-Cerrahpaşa

Istanbul, Turkey (Türkiye)

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NCT07230236


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