RecruitingNot ApplicableNCT07231822

The Investigation of the Effectiveness of Virtual Reality Applications in Postmenopausal Osteoporosis Patients

The Investigation of the Effectiveness of Virtual Reality Applications in Postmenopausal Osteoporosis Patients: A Randomized Controlled Trial


Sponsor

Kirsehir Ahi Evran Universitesi

Enrollment

50 participants

Start Date

Nov 20, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Osteoporosis is a progressive disease characterised by a decrease in bone mass, deterioration in bone microarchitecture, and increased fragility. Etiologically, it is divided into two types: primary (postmenopausal and senile) and secondary. Postmenopausal women are particularly at high risk; it is seen in more than 80% of women over the age of 50 and in almost all individuals over the age of 75. With menopause, bone mineral density decreases, which negatively affects neuromuscular functions, leading to balance disorders, decreased walking speed, and an increased risk of falls. Falls are the primary cause of osteoporotic fractures and result in functional loss, morbidity, mortality, and increased healthcare costs. Exercise is effective in reducing bone loss; in recent years, therapeutic virtual reality and exercise games (exergames) have come to the fore. However, the literature on the effectiveness of these applications in postmenopausal osteoporosis patients is limited. The aim of this study is to investigate the effects of virtual reality applications on balance, quality of life, and fall risk and to compare them with a control group.


Eligibility

Min Age: 40 YearsMax Age: 65 Years

Inclusion Criteria6

  • Postmenopausal women aged 50-75 years
  • Individuals diagnosed with osteoporosis based on Dual-Energy X-ray Absorptiometry (DEXA) measurement (T-score ≤ -2.5)
  • Having been in menopause for at least 1 year
  • Being able to walk independently (without the use of assistive devices)
  • Volunteering to participate in the study and having provided informed consent
  • Having adequate cognitive function (e.g., Mini Mental Test ≥ 24)

Exclusion Criteria6

  • Secondary osteoporosis diagnosis (e.g. endocrine, metabolic or drug-induced causes)
  • History of lower limb fracture or surgical intervention within the last 6 months
  • Individuals with severe cardiovascular, neurological, or musculoskeletal disorders
  • Individuals with vestibular or visual impairments that may affect balance
  • Intolerance to virtual reality applications (e.g., dizziness, nausea, etc.)
  • Individuals who have participated in a regular physiotherapy or exercise programme within the last 3 months

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Interventions

OTHERConventional treatment

Traditional treatment will consist of posture exercises aimed at ensuring proper posture, strengthening exercises, balance exercises, patient education aimed at preventing falls and fractures, aerobic exercises, and interventions aimed at controlling acute and chronic pain and restoring independence in daily living activities.

OTHERVirtual reality treatment

Virtual reality applications will consist of videos and video-based games (exergames). Should an application pose a risk to patients, the programme will be reviewed.


Locations(1)

Kırşehir Ahi Evran University

Center, Kirşehi̇r, Turkey (Türkiye)

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NCT07231822


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