A Phase II Trial of SHR-3045 Injection in Patients With Rheumatoid Arthritis

This study is testing a new injectable drug called SHR-3045 for people with moderate-to-severe active rheumatoid arthritis (RA) — a chronic autoimmune disease that causes painful, swollen joints. Researchers want to see how well and how safely it works in people who haven't responded to other RA treatments. **You may be eligible if...** - You are between 18 and 75 years old - You have been diagnosed with moderate-to-severe active rheumatoid arthritis - At least one prior RA treatment (conventional or biologic) has not worked well enough or caused intolerable side effects - Your weight and BMI are within study requirements **You may NOT be eligible if...** - You are under 18 or over 75 years old - Your RA is mild or currently well controlled - You have active serious infections (e.g., tuberculosis, hepatitis) - You have had recent major surgery, a heart event, or cancer - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.