RecruitingNot ApplicableNCT07233980

Therapist-Guided Internet-Delivered CBT for Chronic Conditions: Predictors of Change

Therapist-Guided Internet-Delivered Cognitive Behaviour Therapy (CBT) for Chronic Conditions (Chronic Conditions Course; CCC): Single-Group Predictors of Change in Routine Care


Sponsor

University of Regina

Enrollment

260 participants

Start Date

Oct 8, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Chronic health conditions are common, disabling, and often co-occur with depression and anxiety. Internet-delivered cognitive behaviour therapy (ICBT) reduces barriers to treatment and has been adapted for chronic conditions. A transdiagnostic approach is promising because it is both effective and convenient in that clients with diverse conditions receive the same program. Both therapist-guided and self-guided formats have been found effective; however, in routine care therapist support is most common to ensure that clients have support to personalize care. This study evaluates the therapist-guided Chronic Conditions Course (CCC) and examines predictors of change. Past research shows that the most robust predictors of ICBT outcomes are baseline severity, adherence, credibility, and working alliance. However, few studies of ICBT for chronic conditions have examined predictors together. Moreover, the researchers are aware of no studies that have examined these core predictors in routine delivery of ICBT for those with chronic health conditions alongside other predictors-such as changes in thoughts and adaptive actions. A limitation of past work is that predictor analyses were typically secondary to trials designed for other purposes. This study directly addresses that gap by prospectively modeling predictors of change in routine care.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a therapist-guided internet-delivered cognitive behavioral therapy (CBT) program for people in Saskatchewan, Canada, who have a chronic physical health condition — such as chronic pain, diabetes, or heart disease — that is affecting their mental health. The program is delivered entirely online. **You may be eligible if...** - You live in Saskatchewan, Canada - You are 18 or older - You have been diagnosed with a chronic physical health condition that is impacting your mental health - You have access to a computer and the internet - You consent to participate in the research **You may NOT be eligible if...** - You live outside Saskatchewan - You have a current severe psychiatric or medical condition requiring immediate treatment (e.g., active mania, psychosis, suicidal crisis, or urgent surgery) - You are already receiving treatment through this clinic - You have significant cognitive difficulties that would prevent participation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALInternet-delivered CBT - Chronic Conditions Course (CCC)

The Wellbeing Course for Chronic Health Conditions is a transdiagnostic, internet-delivered cognitive behavioral intervention developed at Macquarie University. It is designed to help people living with chronic health conditions develop skills and strategies to maintain quality of life and emotional wellbeing. The course comprises 5 core online lessons released gradually over 8 weeks, targeting symptom identification, challenging unhelpful thoughts, pleasant activity scheduling, activity pacing and graded exposure, and relapse prevention. Each lesson is accompanied by downloadable exercise worksheets, case stories, and additional resources addressing challenges that clients may face alongside their chronic health conditions, such as assertive communication. Lesson materials are presented in a didactic, text-based format with visual supports. Therapists spend approximately 15 minutes each week responding to clients' messages and providing support.


Locations(2)

Online Therapy Unit, University of Regina

Regina, Saskatchewan, Canada

Online Therapy Unit

Regina, Saskatchewan, Canada

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NCT07233980