RecruitingNCT07235527

Real-Life Clinical Outcomes of Aflibercept Biosimilar MY-1701P in the Treatment of Exudative Age-Related Macular Degeneration

Real-World Outcomes of Aflibercept Biosimilar MY-1701P Treatment in Exudative Age-Related Macular Degeneration


Sponsor

Saglik Bilimleri Universitesi

Enrollment

54 participants

Start Date

Nov 20, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

In this study, patients receiving Eylea treatment will be treated with Yesafili, a biosimilar molecule, and routine examination results will be noted.


Eligibility

Min Age: 45 YearsMax Age: 90 Years

Inclusion Criteria3

  • Patients aged between 45 and 90 years with active neovascular age-related macular degeneration (nAMD)
  • who show signs of disease activity on routine ophthalmologic examination and optical coherence tomography (OCT)
  • for whom intravitreal injection has already been clinically indicated

Exclusion Criteria7

  • Patients younger than 45 years or older than 90 years
  • History of stroke, cerebrovascular event, myocardial infarction, or coronary stent placement within the last six months
  • Presence of uveitis
  • Media opacity preventing adequate retinal imaging (e.g., corneal opacity, mature cataract)
  • Coexistence of other retinal vascular diseases (e.g., branch retinal vein occlusion, diabetic macular edema)
  • Presence of hereditary retinal dystrophies
  • Presence of optic atrophy

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Interventions

DRUGAflibercept biosimilar (MY-1701P)

Patients receiving the aflibercept biosimilar MY-1701P (marketed as Yesafili®) as part of routine clinical care.


Locations(1)

Prof. Dr. Cemil Taşcıoğlu City Hospital

Istanbul, şişli, Turkey (Türkiye)

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NCT07235527


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