RecruitingNCT07236203

Predictive Factors for the Efficacy of CD19 CAR-T Therapy in Relapsed/Refractory Large B-Cell Lymphoma: A Clinical Study


Sponsor

Fudan University

Enrollment

80 participants

Start Date

Feb 29, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This is a single-center real-world study aiming to explore predictive factors for the efficacy of CAR-T therapy in patients with relapsed/refractory large B-cell lymphoma (R/R LBCL).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at factors that predict how well CAR-T cell therapy — a type of treatment that engineers a patient's own immune cells to attack cancer — works in people with large B-cell lymphoma (a type of blood cancer) that has come back or not responded to prior treatments. **You may be eligible if...** - You have been confirmed to have large B-cell lymphoma - Your lymphoma has come back or stopped responding after at least two previous rounds of standard treatment - You are planning to receive an approved CAR-T cell therapy product **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have poor ability to follow through with the study - Your doctor determines another condition makes participation unsuitable Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCAR-T

CD19 CAR-T


Locations(1)

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China

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NCT07236203


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