Progression Patterns of Choroidal Venous Alterations
International Multi-centre, Prospective, Longitudinal Cohort to Evaluate the Progression Pattern of Choroidal Venous Alterations
Singapore National Eye Centre
250 participants
Mar 4, 2025
OBSERVATIONAL
Conditions
Summary
This study is about understanding how a condition called pachychoroid changes over time. Pachychoroid refers to an anatomic choroidal characteristic with abnormally thick choroid or abnormally dilated Haller's vessels. Pachychoroid can range from mild forms which does not cause any problems to more serious ones that might cause vision loss.This study will recruit participants with pachychoroid, to learn more about how this condition develops, how it affects people in the long run, and what factors might make it worse.
Eligibility
Inclusion Criteria4
- Adults aged 45 years or older.
- Presence of pachyvessels on ultra-widefield (UWF) imaging in at least one quadrant.
- Willing to undergo pupil dilation, and protocol-required procedures for both eyes
- Willing to provide written informed consent
Exclusion Criteria5
- Presence of disorders of the ocular media which interfere with visual acuity and other ocular assessments during the study period
- Eyes with other ocular pathology such as trauma, inflammation, previous intraocular surgery (except for cataract surgery)
- Systemic diseases that might affect ocular blood flow such as uncontrolled hypertension, autoimmune disease, and haematological disorders
- Pregnant or nursing women
- Persons who are unable to give informed consent
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Locations(4)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07236671