DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy

This study is comparing two anesthesia approaches for patients undergoing laparoscopic (minimally invasive) colon removal surgery. One group will receive a combination of dexmedetomidine (a sedative and pain-reducing drug) plus desflurane (an inhaled anesthetic). Researchers want to see if this combination leads to better recovery and fewer side effects. **You may be eligible if...** - You are 18 to 65 years old - You are in generally good health with no major systemic illness (ASA Physical Status I or II) - You are scheduled for planned (elective) laparoscopic colon surgery - You can give written informed consent **You may NOT be eligible if...** - You have serious heart, liver, or kidney disease - You have COPD or asthma - You regularly take opioid pain medications or psychiatric medications - You have a heart conduction problem (second- or third-degree heart block, or sick sinus syndrome) - You experienced major bleeding or unstable blood pressure during surgery Talk to your doctor to see if this trial is right for you.