SurgiPerito Trial: High-Purity Type-I Collagen for Peritoneal Reconstruction After Cytoreductive Surgery

This study is testing a high-purity collagen patch (SurgiPerito) used to rebuild the lining of the abdominal cavity (peritoneum) after extensive cancer-removal surgery, with the goal of reducing complications and improving healing. **You may be eligible if...** - You are 18 years or older with cancer that has spread to the lining of the abdomen (peritoneal surface cancers — such as colorectal, ovarian, appendiceal, mesothelioma, or pseudomyxoma) - You are undergoing cytoreductive surgery (surgery to remove as much tumor as possible), with or without heated chemotherapy (HIPEC), that requires removal of some of the abdominal lining - You are in reasonable health (ECOG 0–2) with adequate organ function **You may NOT be eligible if...** - You have a known allergy to collagen - You have an active infection - You are on long-term steroids or immune-suppressing medications - You are pregnant or breastfeeding - You have uncontrolled sepsis, a bowel rupture, or major small bowel removal during surgery Talk to your doctor to see if this trial is right for you.