RecruitingNCT07243873

Synthetic PET From CT Improves Precision Diagnosis and Treatment of Lung Cancer: a Prospective, Observational, Multicenter Study


Sponsor

Shanghai Pulmonary Hospital, Shanghai, China

Enrollment

10,000 participants

Start Date

Dec 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to synthesise PET data that preserves biological relevance and adds clinical value to the diagnosis and prognosis of lung cancer by establishing anatomical-to-metabolic mapping based on paired diagnostic CT and FDG-PET scans, thereby prospectively validating the clinical utility of the model.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria2

  • Patients with non-small cell lung cancer scheduled to undergo PET-CT and pathological examinations;
  • Voluntarily participate and sign an informed consent form;

Exclusion Criteria4

  • History of other malignant tumours;
  • Image artefacts;
  • Without pathological diagnostic information;
  • Without paired CT and FDG-PET scan images.

Interventions

DIAGNOSTIC_TESTPET-CT

A PET-CT scan is performed prior to initiating systemic treatment for the tumour.


Locations(5)

Affiliated Hospital of Zunyi Medical University

Zunyi, Guizhou, China

The First Affiliated Hospital of Nanchang University

Jiangxi, Nanchang, China

Shanghai East Hospital

Shanghai, Shanghai Municipality, China

Shanghai Pulmonary Hospital

Shanghai, Shanghai Municipality, China

Ningbo No.2 Hospital

Ningbo, Zhejiang, China

View Full Details on ClinicalTrials.gov

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NCT07243873


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