Effects of Modified CIMT With and Without PNF
Effects of Modified Constraint-induced Movement Therapy With and Without Proprioceptive Neuromuscular Facilitation Techniques on Upper Extremity Function in Pediatric Stroke Patients
Riphah International University
20 participants
Oct 27, 2025
INTERVENTIONAL
Conditions
Summary
This randomized clinical trial investigates the effects of modified CIMT with and without the addition of PNF techniques on upper extremity function in pediatric stroke patients, aiming to determine whether combining these approaches yields superior motor recovery.This study will be conducted as a randomized clinical trial over an intervention period of six-week. 20 pediatric stroke patients with upper extremity impairments will be randomly assigned to two groups: one receiving modified CIMT alone and the other receiving modified CIMT combined with PNF techniques. Pre- and post-intervention assessments will be conducted using standardized measures, such as Pediatric Motor Activity Log(PMAL) for upper extremity function, Modified Ashworth Scale(MAS) and Manual Ability Classification System(MACS). Muscle tone and physical activity status will also be evaluated. Data will be entered and analyzed in SPSS V-26.0 to compare improvements in motor function between the two groups, with statistical significance assessed to determine the efficacy of each intervention
Eligibility
Inclusion Criteria6
- Paeds Patients with confirmed diagnosis of Stroke
- Children between age 5 to 13 years
- Modified Ashworth Scale spasticity level 1 and 2.
- Patients having Manual Ability Classification System Score between 3 to 6.
- GMFCS level 1 and 2
- Patient having in affected upper extremity at least 20◦ of active wrist extension starting from the full flexion, 10◦ of active extension or abduction in the thumb, and 10◦ of active extension in the metacarpophalangeal and interphalangeal joints of the other fingers
Exclusion Criteria2
- Patients with epilepsy or seizure disorder
- Patients with history of botulinum toxin injection, cognitive impairment, fracture and any surgical procedure in upper extremity
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Interventions
Modified CIMT Protocol: Participants wear a mitt on the unaffected hand daily for 5 hours approximately to encourage the use of the affected upper limb. They engage in task-oriented activities designed to improve motor function, hand-eye coordination, and strength of the affected extremity.
PNF (Proprioceptive Neuromuscular Facilitation) is a stretching and rehabilitation technique that combines muscle contraction and relaxation with passive stretching to improve flexibility, range of motion, and muscle control
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07244042