IV Magnesium in the Treatment of Acute Dysmenorrhea
Evaluation of Intravenous Magnesium Administration in the Treatment of Dysmenorrhea
Havva Betül Bacak
60 participants
Jul 1, 2025
INTERVENTIONAL
Conditions
Summary
This prospective, randomized, double-blind clinical trial aims to evaluate the analgesic efficacy of intravenous magnesium sulfate in women presenting to the emergency department with acute dysmenorrhea. Participants will be randomized into two groups receiving either 2 ampoules of magnesium sulfate or intravenous dexketoprofen. Pain levels will be assessed using the Visual Analog Scale (VAS) before and after treatment.
Eligibility
Inclusion Criteria5
- Female patients aged 18 to 35 years
- Presenting to the obstetrics and gynecology emergency department with a diagnosis of primary dysmenorrhea
- Having regular menstrual cycles within the last 6 months
- Having a Visual Analog Scale (VAS) pain score of ≥6 at emergency admission
- Providing written informed consent for participation in the study
Exclusion Criteria7
- Patients with secondary dysmenorrhea or underlying gynecological pathology
- Pregnancy or breastfeeding
- Use of analgesics or muscle relaxants within the last 3 days
- Known allergy to magnesium sulfate or dexketoprofen trometamol
- History of renal failure, cardiac arrhythmia, or serious systemic disease
- Inability to assess pain due to mental disability or communication disorder
- Failure to provide informed consent for participation in the study
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Interventions
Intravenous administration of 2 ampoules (8 ml total) of magnesium sulfate diluted in 100 ml normal saline, infused over 15 minutes.
Intravenous administration of 50 mg dexketoprofen diluted in 100 ml normal saline, infused over 15 minutes.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07248540