The Role of Microbiota in Pancreatic Cancer and Precursor Lesions
Herlev Hospital
300 participants
Nov 1, 2025
OBSERVATIONAL
Conditions
Summary
This is a prospective observational study aiming to investigate the microbiome in patients suspected of having pancreatic cancer. The purpose is to enhance diagnostic accuracy by developing screening protocols for high-risk individuals, identifying specific microbial biomarkers, and improving prognostic criteria to optimize treatment response. Participants will be asked to complete a questionnaire, provide oral and fecal swabs, and-if clinically indicated-1-2 pancreatic biopsies will be collected.
Eligibility
Inclusion Criteria3
- Patients with a suspected lesion (solid/cystic) in the pancreas undergoing diagnostic or therapeutic endoscopic procedure
- Age of 18 years or above
- Signed informed consent form
Exclusion Criteria1
- Contraindications for endoscopic or surgical procedure, such as uncorrected coagulopathy
Interventions
Aprox. 300 patients suspected of pancreatic cancer. Of those, minimum of 50 patients with histologically confirmed PDAC in each of the stages I-II, III and IV, as some of the participants will be diagnosed with a non-malignant disease and will constitute the control group.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07250100