RecruitingNot ApplicableNCT07250581

A Randomized Trial of Annular Repair With Discectomy Versus Discectomy Alone for Lumbar Disc Herniation

Endoscopic Discectomy With Repair of Annulus Fibrosus Versus Discectomy Alone for Lumber Disc Herniation:A Prospective Multicenter Randomized Controlled Trial


Sponsor

The Affiliated Hospital of Qingdao University

Enrollment

300 participants

Start Date

Aug 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to explore the indications and application scope of spinal endoscopy combined with annulus fibrosus repair technology, with a focus on verifying the effectiveness of annulus fibrosus suture technology and evaluating its safety, so as to further support the promotion of annulus fibrosus repair technology in patients with lumbar disc herniation.


Eligibility

Min Age: 12 YearsMax Age: 65 Years

Inclusion Criteria5

  • Age: 12 years old to 65 years old, gender not limited;
  • Diagnosed with Lumbar disc herniation;
  • Preoperative intervertebral disc MRI Pfirrmann grade I - II;
  • Conservative treatment is ineffective, and the symptoms significantly affect life;
  • Be able to cooperate with long-term follow-up and sign the informed consent form.

Exclusion Criteria5

  • Accompanied by lumbar spondylolisthesis, lumbar instability and other lumbar diseases, etc.
  • Previous history of lumbar spine surgery;
  • Those who have other major physical diseases and are unable to tolerate surgery;
  • Diseases such as malnutrition, abnormal bone metabolism, and autoimmune diseases that may affect the postoperative development process;
  • Unable to accept regular follow-up visitors

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Interventions

PROCEDURERepair of the annulus fibrosus

Suture the incision of the annulus fibrosus


Locations(1)

Affiliated Hospital of Qingdao University

Qingdao, China

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NCT07250581