RecruitingNot ApplicableNCT07263074

Considering alloHCT: Opportunities for Patient Reflection During Decision-Making Via Digital Stories

Feasibility and Preliminary Efficacy of a Digital Story Intervention to Facilitate Decision-Making in Patients With Myeloid Cancers Considering Allogeneic Hematopoietic Cell Transplantation

Sponsor

University of Rochester

Enrollment

120 participants

Start Date

Jan 15, 2026

Study Type

INTERVENTIONAL

Conditions

Myeloid Malignancy

Summary

This is a two-arm pilot randomized trial that assesses the feasibility and preliminary efficacy of a digital story and values clarification intervention (Considering alloHCT: Opportunities for Patient Reflection During Decision-Making via Digital Stories \[CHORDS\]) compared to usual care among patients with myeloid cancers considering allogeneic hematopoietic cell transplantation (alloHCT).

Eligibility

Min Age: 21 Years

Inclusion Criteria12

Patients
Age \>21 years old
Diagnosis of myeloid cancer (AML, MDS, myelofibrosis, CML, or MDS/MPN)
Being considered for alloHCT
Able to provide informed consent
Able to speak English. The reason for this is because the digital stories have been created in the English language and their multimedia form cannot easily be translated.
Age \>18 years old
Selected by the patient when asked if there is a "family member, partner, friend or caregiver with whom you discuss or who can be helpful in health-related matters."
Caregiver may be paid/professional or informal caregiver
Able to provide informed consent
Able to speak English
\) Hematologists of the patients who agree to enroll on the study who are part of Wilmot Cancer Institute.

Exclusion Criteria4

Caregivers
\) None
Hematologists
\) None

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Interventions

OTHERCHORDS

The CHORDS intervention consists of 1) digital stories created by individuals who previously underwent consultation for alloHCT and 2) explicit values clarification exercises designed to help patients reflect on their emotions and clarify what matters to them, including a) an interactive workbook, and b) best-worst scaling (BWS).