RecruitingPhase 3NCT07265830

Building Adaptive School-based Interventions for Caries

The Building Adaptive School-based Interventions for Caries Study (BASICS): A Phase III Sequential, Multiple-Assignment, Randomized Trial of Minimally Invasive Therapies to Reduce Treatment Nonresponse

Sponsor

University of Pennsylvania

Enrollment

1,200 participants

Start Date

Aug 18, 2026

Study Type

INTERVENTIONAL

Conditions

Dental Caries

Summary

Dental caries (tooth decay) is the world's most prevalent noncommunicable disease. Current preventive and therapeutic treatments are available that can be provided in a school-based health service environment. However, not all children respond to care, and school programs can result in under- or over-treatment, leaving children at high risk. The Building Adaptive School-based Interventions for Caries (BASICS) study will identify the optimal sequence and intensity of these treatments to minimize nonresponse, creating adaptive interventions tailored to specific needs in order to personalize school-based dental medicine.

Eligibility

Min Age: 5 YearsMax Age: 13 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Fluoride Varnishes, a medical device called Glass Ionomer Sealant, and others for people with dental caries. The study is currently recruiting participants at 1 location. People eligible for this study include aged 5 Years to 13 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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