Efficacy in Preventing Hypertrophic Scars: A Randomised Controlled Trial Comparing Chitosan Cream, Silicone Gel & Olive Oil
Universiti Sains Malaysia
120 participants
Dec 21, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to compare the efficacy of three different topical applications in preventing hypertrophic scars in adults with scars healed after suturing. The main question it aims to answer is: Is Chitosan cream effective in preventing hypertrophic scars? Researchers will compare Chitosan cream with silicone gel and olive oil to see if there is any difference in their efficacies. Participants will be randomly assigned to three groups, with each group using a different topical application. They will be instructed to: * apply the topical application on their scar twice a day for 8 weeks * attend follow-up visits at 4, 12 and 24 weeks for a doctor to assess their scar and take clinical photographs * immediately inform the researcher if they experience any side effects
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Application of Chitosan cream twice daily for 8 weeks
Application of silicone gel twice a day for 8 weeks
Application of olive oil twice daily for 8 weeks
Locations(3)
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For the most up-to-date information, visit the official listing.
NCT07269093