Blood Pressure Control With Thiazide Diuretics in Peritoneal Dialysis Patients

This study is testing whether a type of diuretic (water pill) called a thiazide can help control high blood pressure in patients who are on peritoneal dialysis — a home-based kidney replacement therapy where fluid is cycled through the abdomen. Many dialysis patients retain some kidney function that thiazides may be able to target. **You may be eligible if...** - You are currently on chronic peritoneal dialysis - You have uncontrolled high blood pressure (systolic above 140 mmHg or diastolic above 90 mmHg) **You may NOT be eligible if...** - Your life expectancy is less than 3 months - You are planning to switch to hemodialysis or receive a kidney transplant within 3 months - You have a known allergy to thiazide diuretics - You have a condition that makes thiazide use unsafe Talk to your doctor to see if this trial is right for you.