RecruitingNot ApplicableNCT07271615
Effect of Preoperative Stellate Ganglion Block on Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting
Preoperative Stellate Ganglion Block Reduce the Incidence of Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting: A Prospective, Randomized Controlled Pilot Trial
Sponsor
Xijing Hospital
Enrollment
60 participants
Start Date
Nov 19, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
The primary objective of this study is to determine the feasibility of preoperative stellate ganglion block in reducing the incidence of postoperative atrial fibrillation in patients undergoing CABG.
Eligibility
Min Age: 18 Years
Inclusion Criteria3
- more than 18 years old
- undergoing CABG
- Provide informed consent
Exclusion Criteria11
- History of prior cardiac surgery or atrial fibrillation ablation;
- Emergency coronary artery bypass grafting (CABG);
- Concomitant cardiac procedures (e.g., congenital heart disease repair, left ventricular reconstruction, valve surgery, or aortic surgery);
- Critical preoperative status requiring mechanical or pharmacological support before CABG;
- Left ventricular ejection fraction (LVEF) \<35%;
- History of atrial fibrillation (defined as a supraventricular tachyarrhythmia characterized by rapid and irregular atrial electrical activity);
- Significant mitral valve disease (mitral valve area \<1.5 cm² or regurgitant jet area \<4 cm²), significant aortic valve disease (valve area \<1.5 cm² or regurgitant jet-to-left ventricular outflow tract ratio \>25%);
- Severe left atrial enlargement (left atrial anteroposterior diameter \>55 mm);
- Poorly controlled hyperthyroidism;
- Conditions requiring radiotherapy, chemotherapy, or long-term hormonal therapy;
- Patients with known clinical contraindications to stellate ganglion block (SGB).
Interventions
PROCEDUREStellate Ganglion Block
Ultrasound-guided stellate ganglion block with ropivacaine
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07271615