RecruitingNCT07272213

Thyroid-Stimulating Hormone Levels in Pregnancy and Their Association With Depression, Anxiety, and Sexual Function

Evaluation of the Effects of Thyroid-Stimulating Hormone (TSH) Levels in Pregnancy on Depression, Anxiety, and Sexual Function


Sponsor

Gaziosmanpasa Research and Education Hospital

Enrollment

180 participants

Start Date

Nov 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This prospective, single-center, observational cross-sectional study aims to evaluate the relationship between thyroid-stimulating hormone (TSH) levels and psychological as well as sexual health outcomes during pregnancy. Pregnant individuals will undergo psychometric assessment using the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), the Arizona Sexual Experience Scale (ASEX), and the YKK-13 Quality of Life Scale. The study will investigate whether maternal TSH levels are associated with depression, anxiety, sexual function, and overall quality of life scores. Eligible participants will be pregnant women aged 18-45 years with a singleton pregnancy of at least 6 weeks, who are literate and have provided informed consent. Individuals with a prior psychiatric history, multiple gestation, or existing systemic or endocrine diseases will be excluded. The primary endpoint of the study is to determine the association between TSH levels and psychometric scale scores during pregnancy.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This study is examining whether thyroid hormone levels (specifically TSH — thyroid-stimulating hormone) in pregnancy are linked to depression, anxiety, and sexual function. Researchers are looking at how thyroid function connects with mental health and wellbeing in pregnant women. **You may be eligible if...** - You are a pregnant woman between 18 and 45 years old - You are carrying a single baby - You are at least 6 weeks pregnant - You have had a TSH blood test within the past 4 weeks - You are able to read and complete questionnaires **You may NOT be eligible if...** - You are carrying twins or more - You have a known thyroid condition already being treated - You have severe psychiatric illness that prevents questionnaire completion - You are unable to give informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

SBÜ Gaziosmanpaşa Training and Research Hospital

Istanbul, Gaziosmanpaşa, Turkey (Türkiye)

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NCT07272213