The Effect of Prolonged Sugar-Free Chewing Gum Mastication on Self-Reported Fatigue Levels and Changes of Static and Dynamic Surface Electromyography Parameters in Young Individuals With and Without Temporomandibular Joint Disorders.
Effect of Sugar-Free Chewing Gum Mastication on Fatigue of the Masticatory Muscles in Young Adults With and Without Temporomandibular Joint Disorders
University of Milan
30 participants
Oct 1, 2025
OBSERVATIONAL
Conditions
Summary
This case-control study investigates fatigue induced by prolonged gum mastication in individuals with temporomandibular disorders (TMD). The study addresses two primary questions: How does self-reported fatigue, measured with a visual analogue scale (VAS), change during sustained chewing? How do static and dynamic surface electromyographic (sEMG) parameters evolve over the same period? Participants with TMD will be compared with healthy controls to determine group differences in perceived fatigue and EMG responses. All participants will undergo baseline EMG assessment, then chew sugar-free gum continuously for 3 minutes, alternating sides without rest. After each 3-minute interval, static and dynamic EMG recordings will be obtained and participants will rate their fatigue on the VAS. This cycle may be repeated up to six times (maximum 18 minutes). Participants are free to stop chewing at any time if fatigue becomes intolerable.
Eligibility
Inclusion Criteria6
- Age 19-35 years
- Chewing-gum users, even occasional
- Good general health
- Good oral health
- \- no diagnosed temporomandibular joint disorders
- \- diagnosed temporomandibular joint disorders
Exclusion Criteria9
- Non chewing gum users
- History of neurological disorders
- History of musculoskeletal diseases
- History of facial or cervical injuries
- Presence of cervical pain
- Two or more missing teeth
- Current treatment with fixed or removable orthodontic appliances
- Active periodontal disease
- Presence of cavitated carious lesions
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
The chewing task will last for a maximum of 18 minutes.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07273123