Combined Subcostal and Lateral Transversus Abdominis Plane Block for Postoperative Analgesia Versus Thoracic Epidural Analgesia in Patients Undergoing Major Abdominal Cancer Surgery
Safety and Efficacy of Combined Subcostal and Lateral Transversus Abdominis Plane Block for Postoperative Analgesia Versus Thoracic Epidural Analgesia in Patients Undergoing Major Abdominal Cancer Surgery
Assiut University
50 participants
Dec 10, 2025
INTERVENTIONAL
Conditions
Summary
This study aims to evaluate the safety and efficacy of combined subcostal and lateral transversus abdominis plane (TAP) for postoperative analgesia versus thoracic epidural anesthesia (TEA) in patients undergoing major abdominal cancer surgery.
Eligibility
Inclusion Criteria4
- Age ≥ 18 years.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status I-III.
- Scheduled for major abdominal surgeries including: (e.g., gastrectomy, colectomy, hepatectomy, cystectomy, total abdominal hysterectomy, Nephrectomy, pancreatectomy).
Exclusion Criteria8
- Intraoperative hemodynamic instability.
- History or evidence of coagulopathy.
- Infection or abdominal wall masses at injection site.
- Morbid obesity.
- Other Medical conditions including mental illness or substance abuse.
- Known allergy to local anesthetics.
- Chronic opioid use or chronic pain conditions.
- Pregnancy.
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Interventions
Patients will receive an ultrasound-guided combined subcostal and lateral transversus abdominis plane block.
Patients will receive an ultrasound-guided thoracic epidural anesthesia.
Locations(1)
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NCT07273136