Inspiratory Muscle Training in Patients With Inflammatory Myopathy
The Effect of Inspiratory Muscle Training on the Functional Status of Patients With Inflammatory Myopathy
Józef Piłsudski University of Physical Education
33 participants
Aug 12, 2024
INTERVENTIONAL
Conditions
Summary
Inflammatory myopathies are rare autoimmune diseases leading to progressive muscle weakness, often including the respiratory muscles. This study aims to investigate whether inspiratory muscle training (IMT) using a threshold device can improve functional status in patients with inflammatory myopathy. Thirty-three patients will undergo a 3-month home-based IMT program with progressive resistance. Functional capacity, inspiratory muscle strength, lung function, diaphragmatic mobility, fatigue, and quality of life will be assessed at baseline and during follow-up. The primary hypothesis is that IMT will enhance inspiratory muscle strength and translate into better functional performance and quality of life.
Eligibility
Inclusion Criteria5
- Diagnosis of inflammatory myopathy according to European Alliance of Associations for Rheumatology / American College of Rheumatology criteria
- Age ≥ 18 years
- Stable clinical condition allowing participation in physical activity
- Ability to understand and follow instructions
- Written informed consent to participate in the study
Exclusion Criteria7
- Cognitive impairment preventing proper exercise performance
- Current respiratory tract infection
- Previous respiratory muscle training within the last 12 months
- History of spontaneous pneumothorax
- Pulmonary hypertension
- Tympanic membrane rupture or other middle ear pathology
- Lack of voluntary and informed consent
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Interventions
Inspiratory muscle training performed with a threshold loading device (Threshold IMT, Philips Respironics). Participants perform 30 breaths once daily, 7 days per week, for 3 months. The training load is set at 30% of maximal inspiratory pressure (MIP) and increased by 10% if the perceived exertion decreases on two consecutive training days. Participants receive individualized instruction and regular follow-up consultations (every 2 weeks) to adjust load and verify adherence.
Locations(1)
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NCT07274267