JMT106 Injection in the Treatment of Advanced Solid Tumors

This trial is testing a new treatment called JMT106 injection for people with advanced solid tumors (cancers of organs or tissues) that have not responded to previous treatments. Researchers want to find out if it is safe and effective. **You may be eligible if...** - You are 18 or older - You have an advanced solid tumor confirmed by biopsy - At least one prior treatment has not worked, or no standard treatment is available - Your cancer can be measured on a scan - You are in fairly good physical condition (ECOG 0–1) - Your blood counts, kidney, and liver function meet required levels **You may NOT be eligible if...** - You have previously received a treatment specifically targeting GPC3 (a protein on cancer cells) - You have active or growing brain metastases (except previously treated, stable ones) - You are on long-term steroids or immune-suppressing medications - You recently had another cancer drug within 4 weeks - You have a history of severe immune reactions to prior cancer therapy - You have active HIV, hepatitis B or C (with detectable virus), or active tuberculosis - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.